Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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Electron Transport Chain (GO:0022900) Genes Targeted by hsa-mir-590-3p in B-CLL Leukemia Haslinger Cluster 17 Table contains all genes in the B-CLL Leukemia Haslinger cluster number 17. If a gene harbors a predicted miRNA binding site by one of the three inference methods it is displayed in the final column: M = Weeder-miRvestigator predicted site, P = PITA predicted site and T = TargetScan predicted site. Entrez ID Symbol Description hsa-mir-590-3p GO:0022900 1353 COX11 COX11 cytochrome c oxidase assembly homolog (yeast) [Source:HGNC Symbol;Acc:2261] T 55916 NXT2 nuclear transport factor 2-like export factor 2 [Source:HGNC Symbol;Acc:18151] P T 143 PARP4 poly (ADP-ribose) polymerase family, member 4 [Source:HGNC Symbol;Acc:271] T 2628 GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) [Source:HGNC Symbol;Acc:4175] T 10989 IMMT inner membrane protein, mitochondrial [Source:HGNC Symbol;Acc:6047] zzz999 2108 ETFA electron-transfer-flavoprotein, alpha polypeptide [Source:HGNC Symbol;Acc:3481] zzz999 Yes 115201 ATG4A ATG4 autophagy related 4 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:16489] zzz999 2968 GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa [Source:HGNC Symbol;Acc:4658] zzz999 10951 CBX1 chromobox homolog 1 [Source:HGNC Symbol;Acc:1551] P T 221656 KDM1B lysine (K)-specific demethylase 1B [Source:HGNC Symbol;Acc:21577] P T 201562 PTPLB protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b [Source:HGNC Symbol;Acc:9640] P 11234 HPS5 Hermansky-Pudlak syndrome 5 [Source:HGNC Symbol;Acc:17022] T 80777 CYB5B cytochrome b5 type B (outer mitochondrial membrane) [Source:HGNC Symbol;Acc:24374] P T Yes 175 AGA aspartylglucosaminidase [Source:HGNC Symbol;Acc:318] zzz999 10617 STAMBP STAM binding protein [Source:HGNC Symbol;Acc:16950] zzz999 26751 SH3YL1 SH3 domain containing, Ysc84-like 1 (S. cerevisiae) [Source:HGNC Symbol;Acc:29546] T 9801 MRPL19 mitochondrial ribosomal protein L19 [Source:HGNC Symbol;Acc:14052] T 23741 EID1 EP300 interacting inhibitor of differentiation 1 [Source:HGNC Symbol;Acc:1191] P T 466 ATF1 activating transcription factor 1 [Source:HGNC Symbol;Acc:783] P T 5162 PDHB pyruvate dehydrogenase (lipoamide) beta [Source:HGNC Symbol;Acc:8808] T 7915 ALDH5A1 aldehyde dehydrogenase 5 family, member A1 [Source:HGNC Symbol;Acc:408] T Yes 10329 TMEM5 transmembrane protein 5 [Source:HGNC Symbol;Acc:13530] zzz999 8766 RAB11A RAB11A, member RAS oncogene family [Source:HGNC Symbol;Acc:9760] zzz999 5569 PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha [Source:HGNC Symbol;Acc:9017] zzz999 6451 SH3BGRL SH3 domain binding glutamic acid-rich protein like [Source:HGNC Symbol;Acc:10823] P T 5889 RAD51C RAD51 homolog C (S. cerevisiae) [Source:HGNC Symbol;Acc:9820] T 821 CANX calnexin [Source:HGNC Symbol;Acc:1473] T 10146 G3BP1 GTPase activating protein (SH3 domain) binding protein 1 [Source:HGNC Symbol;Acc:30292] P T 8930 MBD4 methyl-CpG binding domain protein 4 [Source:HGNC Symbol;Acc:6919] zzz999 8895 CPNE3 copine III [Source:HGNC Symbol;Acc:2316] T 11051 NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 [Source:HGNC Symbol;Acc:13870] P T 9588 PRDX6 peroxiredoxin 6 [Source:HGNC Symbol;Acc:16753] zzz999 10092 ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa [Source:HGNC Symbol;Acc:708] T 2224 FDPS farnesyl diphosphate synthase [Source:HGNC Symbol;Acc:3631] zzz999 5450 POU2AF1 POU class 2 associating factor 1 [Source:HGNC Symbol;Acc:9211] zzz999 3032 HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit [Source:HGNC Symbol;Acc:4803] zzz999 55699 IARS2 isoleucyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:29685] zzz999 23300 ATMIN ATM interactor [Source:HGNC Symbol;Acc:29034] T 4065 LY75 lymphocyte antigen 75 [Source:HGNC Symbol;Acc:6729] T 6902 TBCA tubulin folding cofactor A [Source:HGNC Symbol;Acc:11579] P T 4087 SMAD2 SMAD family member 2 [Source:HGNC Symbol;Acc:6768] P T 9793 CKAP5 cytoskeleton associated protein 5 [Source:HGNC Symbol;Acc:28959] P T 6342 SCP2 sterol carrier protein 2 [Source:HGNC Symbol;Acc:10606] P 57037 ANKMY2 ankyrin repeat and MYND domain containing 2 [Source:HGNC Symbol;Acc:25370] zzz999 5573 PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) [Source:HGNC Symbol;Acc:9388] T 22948 CCT5 chaperonin containing TCP1, subunit 5 (epsilon) [Source:HGNC Symbol;Acc:1618] zzz999 11342 RNF13 ring finger protein 13 [Source:HGNC Symbol;Acc:10057] zzz999 11311 VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:14579] zzz999 9738 zzz999 Centrosomal protein CP110 [Source:UniProtKB/Swiss-Prot;Acc:O43303] T 5824 PEX19 peroxisomal biogenesis factor 19 [Source:HGNC Symbol;Acc:9713] T 2926 GRSF1 G-rich RNA sequence binding factor 1 [Source:HGNC Symbol;Acc:4610] P T 54499 TMCO1 transmembrane and coiled-coil domains 1 [Source:HGNC Symbol;Acc:18188] T 9823 ARMCX2 armadillo repeat containing, X-linked 2 [Source:HGNC Symbol;Acc:16869] zzz999 5437 POLR2H polymerase (RNA) II (DNA directed) polypeptide H [Source:HGNC Symbol;Acc:9195] zzz999 23643 LY96 lymphocyte antigen 96 [Source:HGNC Symbol;Acc:17156] zzz999 4709 NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa [Source:HGNC Symbol;Acc:7698] zzz999 Yes 10284 SAP18 Sin3A-associated protein, 18kDa [Source:HGNC Symbol;Acc:10530] T 9813 KIAA0494 KIAA0494 [Source:HGNC Symbol;Acc:29051] P T 6745 SSR1 signal sequence receptor, alpha [Source:HGNC Symbol;Acc:11323] T 26135 SERBP1 SERPINE1 mRNA binding protein 1 [Source:HGNC Symbol;Acc:17860] T 29969 MDFIC MyoD family inhibitor domain containing [Source:HGNC Symbol;Acc:28870] T 6787 NEK4 NIMA (never in mitosis gene a)-related kinase 4 [Source:HGNC Symbol;Acc:11399] T 80342 TRAF3IP3 TRAF3 interacting protein 3 [Source:HGNC Symbol;Acc:30766] zzz999 23064 SETX senataxin [Source:HGNC Symbol;Acc:445] P T 9666 DZIP3 DAZ interacting protein 3, zinc finger [Source:HGNC Symbol;Acc:30938] T 953 ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 [Source:HGNC Symbol;Acc:3363] P T 10184 LHFPL2 lipoma HMGIC fusion partner-like 2 [Source:HGNC Symbol;Acc:6588] P T 548645 DNAJC25 DnaJ (Hsp40) homolog, subfamily C , member 25 [Source:HGNC Symbol;Acc:34187] P T 55973 BCAP29 B-cell receptor-associated protein 29 [Source:HGNC Symbol;Acc:24131] T 5636 PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2 [Source:HGNC Symbol;Acc:9467] zzz999 2132 EXT2 exostosin 2 [Source:HGNC Symbol;Acc:3513] P T 3073 HEXA hexosaminidase A (alpha polypeptide) [Source:HGNC Symbol;Acc:4878] zzz999 522 ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 [Source:HGNC Symbol;Acc:847] T Yes 9122 SLC16A4 solute carrier family 16, member 4 (monocarboxylic acid transporter 5) [Source:HGNC Symbol;Acc:10925] T 11325 DDX42 DEAD (Asp-Glu-Ala-Asp) box polypeptide 42 [Source:HGNC Symbol;Acc:18676] T 8405 SPOP speckle-type POZ protein [Source:HGNC Symbol;Acc:11254] zzz999 9070 ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) [Source:HGNC Symbol;Acc:744] zzz999 7586 ZKSCAN1 zinc finger with KRAB and SCAN domains 1 [Source:HGNC Symbol;Acc:13101] T 1389 CREBL2 cAMP responsive element binding protein-like 2 [Source:HGNC Symbol;Acc:2350] zzz999 51103 NDUFAF1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 [Source:HGNC Symbol;Acc:18828] zzz999 Yes 6683 SPAST spastin [Source:HGNC Symbol;Acc:11233] T 54765 TRIM44 tripartite motif containing 44 [Source:HGNC Symbol;Acc:19016] zzz999 55972 SLC25A40 solute carrier family 25, member 40 [Source:HGNC Symbol;Acc:29680] zzz999 54429 TAS2R5 taste receptor, type 2, member 5 [Source:HGNC Symbol;Acc:14912] zzz999 23078 KIAA0564 KIAA0564 [Source:HGNC Symbol;Acc:29071] T 2123 EVI2A ecotropic viral integration site 2A [Source:HGNC Symbol;Acc:3499] T 1203 CLN5 ceroid-lipofuscinosis, neuronal 5 [Source:HGNC Symbol;Acc:2076] zzz999 8209 C21orf33 chromosome 21 open reading frame 33 [Source:HGNC Symbol;Acc:1273] zzz999 1380 CR2 complement component (3d/Epstein Barr virus) receptor 2 [Source:HGNC Symbol;Acc:2336] T 10097 ACTR2 ARP2 actin-related protein 2 homolog (yeast) [Source:HGNC Symbol;Acc:169] T 64689 GORASP1 golgi reassembly stacking protein 1, 65kDa [Source:HGNC Symbol;Acc:16769] zzz999 1687 DFNA5 deafness, autosomal dominant 5 [Source:HGNC Symbol;Acc:2810] T 23478 SEC11A SEC11 homolog A (S. cerevisiae) [Source:HGNC Symbol;Acc:17718] P T 695 BTK Bruton agammaglobulinemia tyrosine kinase [Source:HGNC Symbol;Acc:1133] P T 6938 TCF12 transcription factor 12 [Source:HGNC Symbol;Acc:11623] zzz999 3431 SP110 SP110 nuclear body protein [Source:HGNC Symbol;Acc:5401] T 6480 ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 [Source:HGNC Symbol;Acc:10860] T 8125 ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A [Source:HGNC Symbol;Acc:13233] zzz999 54462 FAM190B family with sequence similarity 190, member B [Source:HGNC Symbol;Acc:29197] T 9325 TRIP4 thyroid hormone receptor interactor 4 [Source:HGNC Symbol;Acc:12310] P T 9131 AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 [Source:HGNC Symbol;Acc:8768] zzz999 3428 IFI16 interferon, gamma-inducible protein 16 [Source:HGNC Symbol;Acc:5395] zzz999 8725 C19orf2 chromosome 19 open reading frame 2 [Source:HGNC Symbol;Acc:13236] P T 10247 HRSP12 heat-responsive protein 12 [Source:HGNC Symbol;Acc:16897] T 440138 ALG11 asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) [Source:HGNC Symbol;Acc:32456] T 1429 CRYZ crystallin, zeta (quinone reductase) [Source:HGNC Symbol;Acc:2419] T 10550 ARL6IP5 ADP-ribosylation-like factor 6 interacting protein 5 [Source:HGNC Symbol;Acc:16937] T 8504 PEX3 peroxisomal biogenesis factor 3 [Source:HGNC Symbol;Acc:8858] P T 34 ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain [Source:HGNC Symbol;Acc:89] T 5877 RABIF RAB interacting factor [Source:HGNC Symbol;Acc:9797] T 2632 GBE1 glucan (1,4-alpha-), branching enzyme 1 [Source:HGNC Symbol;Acc:4180] T 1633 DCK deoxycytidine kinase [Source:HGNC Symbol;Acc:2704] P T 51109 RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) [Source:HGNC Symbol;Acc:17964] T 3312 HSPA8 heat shock 70kDa protein 8 [Source:HGNC Symbol;Acc:5241] P T 10473 HMGN4 high mobility group nucleosomal binding domain 4 [Source:HGNC Symbol;Acc:4989] T 23421 ITGB3BP integrin beta 3 binding protein (beta3-endonexin) [Source:HGNC Symbol;Acc:6157] P T 3693 ITGB5 integrin, beta 5 [Source:HGNC Symbol;Acc:6160] zzz999 154313 C6orf165 chromosome 6 open reading frame 165 [Source:HGNC Symbol;Acc:21405] zzz999 25998 IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase [Source:HGNC Symbol;Acc:17853] T 22849 CPEB3 cytoplasmic polyadenylation element binding protein 3 [Source:HGNC Symbol;Acc:21746] T 8546 AP3B1 adaptor-related protein complex 3, beta 1 subunit [Source:HGNC Symbol;Acc:566] T 6392 SDHD succinate dehydrogenase complex, subunit D, integral membrane protein [Source:HGNC Symbol;Acc:10683] T Yes 81542 TMX1 thioredoxin-related transmembrane protein 1 [Source:HGNC Symbol;Acc:15487] T Yes 27348 TOR1B torsin family 1, member B (torsin B) [Source:HGNC Symbol;Acc:11995] T 10935 PRDX3 peroxiredoxin 3 [Source:HGNC Symbol;Acc:9354] zzz999 23530 NNT nicotinamide nucleotide transhydrogenase [Source:HGNC Symbol;Acc:7863] T 6905 TBCE tubulin folding cofactor E [Source:HGNC Symbol;Acc:11582] T 5274 SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 [Source:HGNC Symbol;Acc:8943] zzz999 10434 LYPLA1 lysophospholipase I [Source:HGNC Symbol;Acc:6737] P T 831 CAST calpastatin [Source:HGNC Symbol;Acc:1515] T 51668 HSPB11 heat shock protein family B (small), member 11 [Source:HGNC Symbol;Acc:25019] zzz999 6647 SOD1 superoxide dismutase 1, soluble [Source:HGNC Symbol;Acc:11179] zzz999 1520 CTSS cathepsin S [Source:HGNC Symbol;Acc:2545] T 2058 EPRS glutamyl-prolyl-tRNA synthetase [Source:HGNC Symbol;Acc:3418] zzz999 140609 NEK7 NIMA (never in mitosis gene a)-related kinase 7 [Source:HGNC Symbol;Acc:13386] zzz999 10466 COG5 component of oligomeric golgi complex 5 [Source:HGNC Symbol;Acc:14857] T 29760 BLNK B-cell linker [Source:HGNC Symbol;Acc:14211] zzz999 8439 NSMAF neutral sphingomyelinase (N-SMase) activation associated factor [Source:HGNC Symbol;Acc:8017] zzz999 23595 ORC3 origin recognition complex, subunit 3 [Source:HGNC Symbol;Acc:8489] zzz999 83941 TM2D1 TM2 domain containing 1 [Source:HGNC Symbol;Acc:24142] zzz999 10632 ATP5L ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G [Source:HGNC Symbol;Acc:14247] zzz999 Yes 10955 SERINC3 serine incorporator 3 [Source:HGNC Symbol;Acc:11699] T 3704 ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [Source:HGNC Symbol;Acc:6176] zzz999 86 ACTL6A actin-like 6A [Source:HGNC Symbol;Acc:24124] T 1666 DECR1 2,4-dienoyl CoA reductase 1, mitochondrial [Source:HGNC Symbol;Acc:2753] zzz999 8450 CUL4B cullin 4B [Source:HGNC Symbol;Acc:2555] T 7095 SEC62 SEC62 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:11846] P T 8674 VAMP4 vesicle-associated membrane protein 4 [Source:HGNC Symbol;Acc:12645] T 10228 STX6 syntaxin 6 [Source:HGNC Symbol;Acc:11441] T 7257 TSNAX translin-associated factor X [Source:HGNC Symbol;Acc:12380] P T 10962 MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 [Source:HGNC Symbol;Acc:16997] zzz999 145389 SLC38A6 solute carrier family 38, member 6 [Source:HGNC Symbol;Acc:19863] zzz999 55856 ACOT13 acyl-CoA thioesterase 13 [Source:HGNC Symbol;Acc:20999] zzz999 2823 GPM6A glycoprotein M6A [Source:HGNC Symbol;Acc:4460] T 404672 GTF2H5 general transcription factor IIH, polypeptide 5 [Source:HGNC Symbol;Acc:21157] zzz999 1207 CLNS1A chloride channel, nucleotide-sensitive, 1A [Source:HGNC Symbol;Acc:2080] zzz999 4200 ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial [Source:HGNC Symbol;Acc:6984] zzz999 9447 AIM2 absent in melanoma 2 [Source:HGNC Symbol;Acc:357] zzz999 2665 GDI2 GDP dissociation inhibitor 2 [Source:HGNC Symbol;Acc:4227] P T 5527 PPP2R5C protein phosphatase 2, regulatory subunit B', gamma [Source:HGNC Symbol;Acc:9311] T 5993 RFX5 regulatory factor X, 5 (influences HLA class II expression) [Source:HGNC Symbol;Acc:9986] zzz999 2744 GLS glutaminase [Source:HGNC Symbol;Acc:4331] T 9111 NMI N-myc (and STAT) interactor [Source:HGNC Symbol;Acc:7854] zzz999 4711 NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa [Source:HGNC Symbol;Acc:7700] T Yes 3155 HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase [Source:HGNC Symbol;Acc:5005] zzz999 865 CBFB core-binding factor, beta subunit [Source:HGNC Symbol;Acc:1539] P T 7360 UGP2 UDP-glucose pyrophosphorylase 2 [Source:HGNC Symbol;Acc:12527] zzz999 2124 EVI2B ecotropic viral integration site 2B [Source:HGNC Symbol;Acc:3500] T 27032 ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 [Source:HGNC Symbol;Acc:13211] T 1615 DARS aspartyl-tRNA synthetase [Source:HGNC Symbol;Acc:2678] P T 10987 COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) [Source:HGNC Symbol;Acc:2240] zzz999 10096 ACTR3 ARP3 actin-related protein 3 homolog (yeast) [Source:HGNC Symbol;Acc:170] zzz999 830 CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 [Source:HGNC Symbol;Acc:1490] P T 51382 ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D [Source:HGNC Symbol;Acc:13527] T 9562 MINPP1 multiple inositol-polyphosphate phosphatase 1 [Source:HGNC Symbol;Acc:7102] zzz999 98 ACYP2 acylphosphatase 2, muscle type [Source:HGNC Symbol;Acc:180] T

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